In order to evaluate the ability of the United States Geophysical Fluid Dynamics Laboratory (GFDL) model to simulate ocean ventilation, three GFDL models (GFDL-ESM2G, GFDL-ESM2M, GFDL-CM3) are used to simulate the data of CFC-11 (CCl3F) in the ocean. The characteristics of sea surface concentration, total water column per unit area, total amount of substance, maximum penetration depth, and vertical cross section (in the Atlantic Ocean, the Pacific Ocean, and the Southern Ocean) of CFC-11 are analyzed. By comparing the simulation results of the GFDL models with the observations of salinity, sea temperature, and CFC-11, the following conclusions are obtained. The high-value centers of CFC-11 at sea surface simulated by the GFDL models are concentrated in high latitudes, such as the North Atlantic and western North Pacific. However, the simulation result in the Ross Sea and the Weddell Sea is 1.5 pmol·kg-1 lower than the observation, which is caused by the negative correlation between the solubility of CFC-11 and sea surface temperature, that is, the solubility of CFC-11 decreases as the sea surface temperature increases. The total amount of substance of CFC-11 in the global oceans simulated by GFDL is higher than the observation, especially the simulation result of CM3 is 22.9% higher than the observation, and the average value of the GFDL models is 15.6% higher than the observation. The analysis of the zonal sections of 46°N in the North Pacific, 24°N in the North Atlantic, and 65°S in the Southern Ocean shows that there is still some room for the GFDL models to improve when simulating some important water masses. For example, the position of the maximum value of CFC-11 concentration simulated by the GFDL models is too deep below 1 000 m in the section of 24°N.