Based on the observation data of CALIPSO spaceborne lidar from June 2006 to October 2021, the spatio-temporal distribution characteristics of clouds affecting flight such as low clouds and deep convection in the Luzon Strait are statistically studied. Under the combined influence of monsoon, solar radiation change, and monsoon trough in the South China Sea, it is concluded as follows. (1) The low cloud coverage is the smallest (2.9%) around August and the largest (67.4%) around January; the average cloud base height of low clouds is the lowest (756.1 m) around July and the highest (1 259.4 m) around January; the average thickness of low clouds reaches its minimum (714.1 m) in July and maximum (1 039.4 m) in December. (2) The probability of deep convection is the smallest (1.9%) around October and the largest (18.7%) in December; the highest top height of deep convection is in October with the average value being 16 056.2 m, and the lowest is in April with the average value being 14 164.0 m.