In recent years, domestic and foreign scholars assess the impacts of climate change on grain production with different methods, and crop mechanism model is one of the widely used methods. With the characteristics of strong mechanism, open source code, and relatively simple way to adjust parameters, the WOFOST (WOrld FOod STudies) model has played an important role in related researches. Based on the growth mechanism of different crops, this model could be used to assess the climatic potential productivity and the impacts of meteorological disasters after applicability verification. Combined with the historical climate data and the future climate scenario data, this model could also be used to quantitatively assess the impacts of the past and future climate change on grain production. On this basis, the general information of the WOFOST model is introduced, including its basic principle, operating mechanism, parameter setting, parameter optimization methods and so on. The research progress of assessing the impacts of climate change on grain production by the WOFOST model is systematically summarized, and the shortcomings of the existing researches are pointed out, hoping to provide reference for future researches.