In this study, the CMA-STI Best Track Dataset for Tropical Cyclones over western North Pacific from 1951 to 2016, NCEP/NCAR reanalysis data, and COBE-SST dataset of NOAA are used. According to tropical cyclone genesis fields, the tropical cyclones are divided into two types: tropical cyclones in the South China Sea and tropical cyclones in western North Pacific. The response of tropical cyclones landing in China during their active period to the Eastern Pacific (EP) type and Central Pacific (CP) type El Niño is investigated by means of synthetic analysis and other statistical methods. The results show the frequency of tropical cyclones in the South China Sea under the two types of El Niño events has little differenc during the tropical cyclones’ active period. The rate of the South China Sea tropical cyclones landing in China for the duration of EP type El Niño is lower and the intensity is weaker than that during CP type El Niño. For the duration of CP type El Niño, the frequency of tropical cyclone formation in western North Pacific is higher than that during EP type El Niño, but the tropical cyclone landfall in China is less and the tropical cyclone intensity is weaker than that during EP type El Niño. However, the difference in the landing rates of tropical cyclones generated over western North Pacific in China during the two types of El Niño events does not pass the significance test. Compared with CP type El Niño events, during EP type El Niño events, the combined action of low sea surface temperature in western North Pacific, poor water vapor conditions in the central troposphere, unusually low vorticity in the lower troposphere, abnormal downdraft in Walker circulation in the sea areas with more tropical cyclone genesis, and the subtropical high over western North Pacific which is more eastward southward, leads to fewer tropical cyclones landing in China.