East Asia is one of the regions with the most potential for development and cooperation, and the El Ni?o-Southern Oscillation (ENSO), as an interannual climate anomaly signal affecting stratospheric ozone, is of scientific and social significance to study its impact on stratospheric ozone in East Asia. In this paper, the linkage between ENSO and stratospheric ozone in East Asia and the mechanism of its influence are explored by using the HadISST dataset and ERA5 reanalysis information from 1979-2021, and the influence of ENSO on the ozone valley of the Tibetan Plateau is investigated. The results show that ENSO mainly affects the ozone content and distribution in the lower stratosphere of East Asia, and influences the stratospheric atmosphere of East Asia through the anomalies of Rossby waves activities, which in turn affects the ozone content and distribution through dynamical effects. ENSO has a significant positive correlation with the ozone content in the lower stratosphere in the ranges of 25-30 °N and 70-120 °E, with differences in the effects on positive and negative phases. The ENSO-induced Rossby waves activities anomalies are dominated by the lower stratospheric influence, with positive phases accompanying Rossby waves upload at low latitudes and affecting East Asia through northwestward wave flux anomalies from the tropical east-central Pacific to East Asia. The wave activity caused the atmosphere in East Asia to undergo meridional shifts and vertical motions, leading to the anomalous ozone content and distribution in this region. In addition, it was found that there is an interdecadal variation in the relationship between ENSO and stratospheric ozone in East Asia from 1979-2021, which is attributed to the change in the spatial correlation pattern between ozone and sea-surface temperature between the two periods.