Based on CMIP6 Climate model and CN05.1 grid observation data, the simulation situation of the extreme temperature indices in the Shandong region by the CMIP6 models is evaluated. Meanwhile, the changing trends of the future extreme temperature indices in Shandong Province under three Shared Socioeconomic Pathways (SSPs) scenarios in different future time periods are predicted, and the spatiotemporal variation characteristics of the extreme temperature indices under different SSPs scenarios are also explored in depth. The estimated results show that, compared with the base period from 1995 to 2014, the annual maximum value of daily maximum temperature (TXx), and annual minimum value of daily minimum temperature (TNn), in Shandong Province will show an upward trend in the future. And the warming of the extreme minimum temperature will be more obvious than that of the extreme maximum temperature. While the number of frost days (FD), andicing days (ID) all show a decreasing trend. From the perspective of spatial distribution, in the future, both the highest value of TXx and the lowest value of TNn will appear in the northwestern region of Shandong Province. The number of FD and ID will be the largest in the northern part of Shandong.